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National Center for Genome Analysis Support

Indiana University Pervasive Technology Institute


The mission of the National Center for Genome Analysis Support is to enable the biological research community of the US to analyze, understand, and make use of the vast amount of genomic information now available. NCGAS focuses particularly on transcriptome- and genome-level assembly, phylogenetics, metagenomics/transcriptomics and community genomics.

In order to carry out its mission, NCGAS provides data analysis support, consulting services, data storage, results archiving, and computational resources for biologists and genomic researchers.

The Center is funded by the NSF to provide the following services:

  • Consulting for biologists undertaking genome analysis
  • Optimization, hardening, and enhancement of genome analysis software
  • Providing to biologists delivery and assistance in use of supercomputer clusters for genome analysis, including many supercomputers and supercomputer clusters that are part of XSEDE (the eXtreme Science and Engineering Discovery Environment). In particular, we support software on and use of:
    • Mason, a large memory supercomputer cluster at IU
    • Blacklight – a shared memory supercomputer run by the Pittsburgh Supercomputing Center. Access to a large memory supercomputer cluster to support genome analysis, particular support of genome assembly software.
    • Long-term storage of data (by default up to 50 TB and with proposals amounts larger than that) and
    • Archiving of public data sets, with Dublin Core metadata so that they can be discovered through web searchers, in IU’s persistent digital archive (based on DSPACE)
    • Aid to researchers preparing grant proposals including providing Letters of Collaboration for your project’s NSF grand submission and partnership agreements that commit NCGAS to aiding your research.
    • NCGAS is particularly well positioned to aid researchers writing proposals to the NSF who could benefit from: help with bioinformatics analyses,  help with software management, access to computing time on federally-funded supercomputers and clusters, or assistance with creating and executing data management plans.
    • Stampede – the largest supercomputer accessible as part of XSEDE. Operated by the Texas Advanced Computing Center

NCGAS is pleased to offer our services to biologists funded by the NSF, or working in areas of research that are funded by the NSF. Many genomics, transcriptomics (RNA-seq), and metagenomics projects qualify for our services – typically provided through NSF funding and delivered at no cost to you – simply by filling out a request form that documents your projects status. All NSF-funded life sciences and NIH-funded RNA-Sequencing projects needing to run the Trinity assembler have priority; other projects are supports with our best-effort, as time allows. 

NCGAS also operates a Galaxy workflow portal that you can use to execute bioinformatics analyses with the Galaxy software.

Follow the navigation bar at left to access NCGAS services or to ask us ask us a question by clicking on “Contact us”



Current News and Events

GenePattern Service at IU

NCGAS funded for continued support of GenePattern service in collaboration with the Broad Institute.

January 9th, 2015 - NCGAS received funding through an RO1 award to the Broad Institute to continue working on the GenePattern project. This project allows users to submit work through a graphical interface that is then deployed on IU servers.

Trinity Galaxy Logo

IU Hosts Trinity Galaxy in partnership with the Broad Institute and NCGAS.

January 7th, 2015 - A new instance of Galaxy was launched on January 7th, 2015 that is to be a public asset for the cancer research community as well as other researchers working with RNA-Seq data. The popular Trinity assembler is available on this instance, along with an FTP server. The Trinity software will be run on Karst in February, 2015. The goal of this project is to allow fast uploads, simultaneous jobs and fast downloads of the assembled transcripts. More tools will be added as the service reaches its full potential.